This exclusive formula is designed to support the balance and absorption of fat-soluble vitamins in the body. Help protect your bones, heart, immune health and much more with Protect+.*
This unique, high-potency formula features:
- 300mcg of a double micro-encapsulated bioactive all-trans K2VITAL Delta MK-7
- 250 mcg (10,000 IU) of vitamin D3
- Efficacious amounts of vitamin A and vitamin E
- AstraGin (astragalus membranaceus and panax notoginseng) to promote maximum absorption and delivery of fat soluble vitamins in the body
Vitamin K2 (MK-7)
Vitamin K2 is an essential nutrient that plays a vital role in many biological processes. Western diets are limited in vitamin K2, so vitamin K2 must be obtained through supplementation as well. K2 activates proteins involved in calcium metabolism, including osteocalcin, controlling the transport and distribution of calcium from arteries and soft tissues into bones.
Among all of the K vitamins, vitamin K2 MK-7 exhibits the best bioavailability and longest half-life, with a half-life of 72 hours compared to two hours observed with K1. Due to its quick uptake and long half-life, K2 MK-7 reaches bones and vessel walls more easily, resulting in more effective activation of proteins, like osteocalcin. Osteocalcin proteins in the body must be activated to distribute calcium to our bones. These proteins are unlocked and activated by all-trans K2 MK-7. Protect+ contains >99% of the double micro-encapsulated bioactive form of vitamin K2 MK-7, identical to the all-trans K2 MK-7 found in nature and is fully bio-active providing the full benefits of vitamin K2 MK-7.
Some supplements containing cis MK-7 are still available on the market, despite it being considered biologically inactive and therefore potentially ineffective. Due to the shape of the molecule, cis MK-7 cannot bind to the sites of enzymes, meaning the vitamin K-dependent proteins remain inactivated. On the other hand, all-trans MK-7 is bioactive, therefore it is important for supplements to include the highest possible percentage of this form of vitamin to achieve the desired health benefits.
Areas of clinical interest and potential roles for MK-7:
Most of the new published research has been with higher dosing featured in Protect+ and has been demonstrating effects on new pathways, proteins, and cells. This includes ATP function in mitochondria, antioxidant effects, cardiovascular function, brain health, gut health, and more.
Recent research suggests that vitamin D supplementation may help promote cellular health and healthy aging. Vitamin D3 works by increasing the amount of calcium absorbed from the small intestine, helping to form and maintain bones. Vitamin D benefits the body by playing a role in immunity and controlling cell growth. Vitamin D has been shown to support biochemical processes linked to aging, including a healthy inflammatory response, autophagy, cell signaling, anti oxidative status and telomere integrity. There is growing evidence of the role Vitamin D may have in protecting against osteoporosis, high blood pressure, immunity, and many other health conditions.
Vitamin A is a nutrient that is essential for many different functions in the human body. Vitamin A, also known as retinol, plays an important role in bone growth, tooth development, reproduction, cell division, gene expression, and regulation of the immune system. Vitamin A is also necessary for the maintenance of healthy skin, eyes, and mucous membranes. Vitamin A deficiency can lead to a number of serious health problems, including blindness, poor wound healing, and increased susceptibility to infections. Vitamin A is also an important antioxidant that may play a role in prevention and healthy aging.
Vitamin E is an important nutrient that offers a range of benefits for the body. Vitamin E acts as an antioxidant, which means it helps to protect other nutrients from damage. For example, vitamin E helps to protect vitamins A and C, as well as essential fatty acids, from destruction. Vitamin E also helps to protect red blood cells from damage. This is important because red blood cells are responsible for carrying oxygen around the body.
AstraGin® is a natural compound derived from the roots of two traditional Chinese herbs: Panax notoginseng and Astragalus membranaceous which contain astragaloside I, II, IV and ginsenoside Rb1. AstraGin® has shown in over a dozen in-vitro studies to improve the absorption of vitamins, amino acids, peptides, folate, glucosamine and other nutrients in Caco-2 cell, the gold standard used by drug companies to study the absorption of new drugs.
Vitamin K2 MK-7:
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- Sato T, Inaba N, Yamashita T. MK-7 and Its Effects on Bone Quality and Strength. Nutrients. 2020 Mar 31;12(4):965. doi: 10.3390/nu12040965. PMID: 32244313; PMCID: PMC7230802.
- Knapen MH, Braam LA, Drummen NE, Bekers O, Hoeks AP, Vermeer C. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial. Thromb Haemost. 2015 May;113(5):1135-44. doi: 10.1160/TH14-08-0675. Epub 2015 Feb 19. PMID: 25694037.
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- Stephensen CB, Lietz G. Vitamin A in resistance to and recovery from infection: relevance to SARS-CoV2. Br J Nutr. 2021 Dec 14;126(11):1663-1672. doi: 10.1017/S0007114521000246. Epub 2021 Jan 20. PMID: 33468263; PMCID: PMC7884725.
- Cantorna MT, Snyder L, Arora J. Vitamin A and vitamin D regulate the microbial complexity, barrier function, and the mucosal immune responses to ensure intestinal homeostasis. Crit Rev Biochem Mol Biol. 2019 Apr;54(2):184-192. doi: 10.1080/10409238.2019.1611734. Epub 2019 May 14. PMID: 31084433; PMCID: PMC6629036.
- Pekmezci D. Vitamin E and immunity. Vitam Horm. 2011;86:179-215. doi: 10.1016/B978-0-12-386960-9.00008-3. PMID: 21419272.
- Casati M, Boccardi V, Ferri E, Bertagnoli L, Bastiani P, Ciccone S, Mansi M, Scamosci M, Rossi PD, Mecocci P, Arosio B. Vitamin E and Alzheimer's disease: the mediating role of cellular aging. Aging Clin Exp Res. 2020 Mar;32(3):459-464. doi: 10.1007/s40520-019-01209-3. Epub 2019 May 3. PMID: 31054115.
- Corina A, Rangel-Zúñiga OA, Jiménez-Lucena R, Alcalá-Díaz JF, Quintana-Navarro G, Yubero-Serrano EM, López-Moreno J, Delgado-Lista J, Tinahones F, Ordovás JM, López-Miranda J, Pérez-Martínez P. Low Intake of Vitamin E Accelerates Cellular Aging in Patients With Established Cardiovascular Disease: The CORDIOPREV Study. J Gerontol A Biol Sci Med Sci. 2019 May 16;74(6):770-777. doi: 10.1093/gerona/gly195. PMID: 30165472.
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Caution: Individuals taking more than 50 mcg (2,000 IU) of Vitamin D per day should have their vitamin D levels monitored. This product is not intended for long term use and should be used under the supervision of your doctor.